Abstract
High blood concentrations of the naturally occurring polyamines have been reported in leukemia, psoriasis, cystic fibrosis and polycythemia rubra vera. Spermidine and spermine inhibit in vitro plate-let aggregation of platelet rich plasma preparations in which ADP and Ristocetin are the agglutinating agents. The proposal is made that these organic cations may modulate in vivo platelet agglutinability.
Original language | English (US) |
---|---|
Pages (from-to) | 257-264 |
Number of pages | 8 |
Journal | Life Sciences |
Volume | 19 |
Issue number | 2 |
DOIs | |
State | Published - Jul 15 1976 |
Externally published | Yes |
ASJC Scopus subject areas
- General Pharmacology, Toxicology and Pharmaceutics
- General Biochemistry, Genetics and Molecular Biology