Polycystic Kidney Disease

Tsung O. Cheng, Carl J. Lavie, Allan L. Klein, James B. Seward, A. Jamil Tajik, Kenneth F. Hossack, Robert W. Schrier, Patricia A. Gabow, Professor A. Carbonara, G. Restagno, W. J. Kimberling, Eli A. Friedman, Jared J. Grantham

Research output: Contribution to journalLetterpeer-review

2 Scopus citations


To the Editor: An increased prevalence of aortic incompetence and mitral-valve prolapse has been described previously in patients with polycystic kidney disease.1 Hossack et al. (Oct. 6 issue)2 reported a large-scale study done on a prospective basis and employing Doppler echocardiography. The authors contend that they found no association between mitral-valve prolapse and hypertension, a frequent complication of polycystic kidney disease. However, there was a history of hypertension in 56 percent of their subjects with polycystic kidney disease, 12 percent of the unaffected family members, and 12 percent of the controls (P<0.0005). Furthermore, their Table 3 showed a systolic blood.

Original languageEnglish (US)
Pages (from-to)737-739
Number of pages3
JournalNew England Journal of Medicine
Issue number11
StatePublished - Mar 16 1989
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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