Portosystemic shunts in children: A 15-year experience

Jean F. Botha, B. Daniel Campos, Wendy J. Grant, Simon P. Horslen, Debra L. Sudan, Byers W. Shaw, Alan N. Langnas

Research output: Contribution to journalArticlepeer-review

41 Scopus citations

Abstract

Background The role of portosystemic shunt (PSS) in children with portal hypertension has changed because of acceptance of liver transplantation and endoscopic hemostasis. We report our experience with PSS, mainly the distal splenorenal shunt, to define its role in the management of variceal bleeding. Study design From 1987 to 2002, 20 children with variceal bleeding after endoscopic therapy underwent PSS. Patient and database records were reviewed. Results There were 14 boys and 6 girls; mean age was 11 years (range 3 to 18 years). Seventeen distal splenorenal and three mesocaval venous interposition shunts were performed. There was no operative mortality, 19 patients were alive at a median followup of 31 months (range 4 to 168 months) without evidence of recurrent gastrointestinal bleeding. One patient underwent transplantation 2 years after PSS and 1 patient died of hepatic failure while awaiting transplantation. The cause of portal hypertension was portal vein thrombosis (n = 13), biliary atresia (n = 3), congenital hepatic fibrosis (n = 2), hepatitis C cirrhosis (n = 1), and Budd-Chiari syndrome (n = 1). Eighteen children were Child-Turcotte-Pugh class A and the remaining two were class B. One patient had two episodes of hematemesis after PSS. Two patients had worsening ascites. One patient had mild encephalopathy and one patient had shunt stenosis requiring angioplasty. Conclusions PSS is a safe and durable therapy for pediatric patients with portal hypertension. Liver transplantation should be reserved for children with poor synthetic function associated with variceal bleeding. PSS may also serve as a bridge to transplantation in patients with preserved hepatic function. PSS, in particular the distal splenorenal shunt, has produced excellent results. This experience challenges the need for alternative forms of portal decompression.

Original languageEnglish (US)
Pages (from-to)179-185
Number of pages7
JournalJournal of the American College of Surgeons
Volume199
Issue number2
DOIs
StatePublished - Aug 2004

Keywords

  • CTP
  • Child-Turcotte-Pugh classification
  • DSRS
  • GI
  • PSS
  • distal splenorenal shunt
  • gastrointestinal
  • portosystemic shunt

ASJC Scopus subject areas

  • Surgery

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