Postmenopausal endometrial patterns and serum estradiol concentrations

A. A.A. Ismail, M. Ramadan, A. Soliman, A. Rahmy, A. Rizk

Research output: Contribution to journalArticle

Abstract

Eighty postmenopausal women were subjected to endometrial biopsy. Inadequate biopsy was recorded in 30 cases. In the remaining cases (n = 50) the correlation between endometrial patterns and serum estradiol (E2) was performed. These cases were presenting with uterine bleeding (n = 38) or minor gynecological symptoms (n = 12). Proliferative endometrium was the predominant endometrial pattern whereas endometrial malignancy was only present in 15.8% of the bleeding cases. Serum E2 was significantly elevated in cases having malignant endometrium or adenomatous hyperplasia compared to cases having other endometrial patterns. Serum E2 measurement is recommended as a simple screening test for the detection of postmenopausal endometrial hyperplasia and/or malignancy.

Original languageEnglish (US)
Pages (from-to)101-105
Number of pages5
JournalInternational Journal of Gynecology and Obstetrics
Volume27
Issue number1
DOIs
StatePublished - Aug 1988
Externally publishedYes

Keywords

  • Postmenopausal E concentrations
  • Postmenopausal endometrial hyperplasia and/or malignancy
  • Postmenopausal endometrium

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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