Postnatal behavioural effects of maternal nicotine exposure in rats


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39 Scopus citations


Abstract— The effects of nicotine on locomotor activity have been studied in neonate rats exposed to nicotine (1.5 mg kg−1 day−1) throughout the gestational period. Both 14 day old male and female offspring demonstrated an increase in spontaneous locomotor activity when compared with saline‐exposed controls. However, systemic administration of (+)‐amphetamine was effective in attenuating the hyperactivity of these nicotine‐exposed pups. 1988 Royal Pharmaceutical Society of Great Britain

Original languageEnglish (US)
Pages (from-to)870-872
Number of pages3
JournalJournal of Pharmacy and Pharmacology
Issue number12
StatePublished - Dec 1988

ASJC Scopus subject areas

  • Pharmacology
  • Pharmaceutical Science

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