Prediction of change in mitral valve area after mitral balloon commissurotomy using cine computed tomography

Matthew L. White, Maleah Grover-Mc Icay, Robert M. Weiss, Byron F. Vandenberg, Trudy L. Burns, Michael D. Winniford, William Stanford, Charles R. Mc Kay

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Rationale and Objectives. Mitral balloon commissurotomy (MBC) can successfully increase the mitral valve area (MVA) in mitral stenosis, but the outcome is variable. In multicenter studies, qualitative echocardiograpliic scores obtained before MBC are only weakly predictive of the increase in MVA after MBC. Methods. To evaluate whether the change in MVA after MBC can be predicted by evaluating mitral valve morphology using cine computed tomography (CT), we studied 12 women with mitral stenosis and 11 female control subjects. Results. In the patients with mitral stenosis, MVA increased from 1.13 ± 0.24 to 1.93 ± 0.56 cm2 (P< .0001) after MBC. A standard echocardiograpliic score assessment of mitral valve morphology before MBC was not associated with the change in MVA after MBC in these patients (P > .20). However, the total mitral valve morphology score evaluated by cine computed tomography was strongly associated with the change in MVA after MBC (r = −.87; P < .0005). In addition, the individual morphologic characteristics of mitral valve mobility {P < .0025), leaflet thickness (P < .05), and subvalvular disease (P < .05) were significant predictors of the change in MVA after MBC. Conclusion. Cine computed tomography may be useful for predicting immediate increases in MVA in patients after MBC and may be helpful for preoperative assessment of these patients.

Original languageEnglish (US)
Pages (from-to)827-833
Number of pages7
JournalInvestigative Radiology
Issue number9
StatePublished - Sep 1994
Externally publishedYes


  • Cine computed tomography
  • Echocardiography
  • Mitral balloon commissurotomy
  • Mitral stenosis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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