Prenatal cocaine exposure fails to modify neurobehavioral responses and the striatal dopaminergic system in newborn rats

Yiu K. Fung, J. A. Reed, Yuen Sum Lau

Research output: Contribution to journalArticle

35 Scopus citations

Abstract

1. 1. The effects of cocaine on locomotor activity and striatal dopaminergic receptors and dopamine turnover were studied in rat pups exposed to cocaine (30 mg/kg/day) throughout the entire gestational period. 2. 2. Prenatal exposure to cocaine did not alter the motor coordination or spontaneous locomotor activity in the offspring. 3. 3. No change in the characteristics of dopaminergic receptors and the rate of dopamine turnover was detected in the striatum.

Original languageEnglish (US)
Pages (from-to)689-693
Number of pages5
JournalGeneral Pharmacology
Volume20
Issue number5
DOIs
StatePublished - 1989

ASJC Scopus subject areas

  • Pharmacology

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