Preparation and characterization of nanofunctionalized alginate/methacrylated gelatin hybrid hydrogels

R. Kadri, G. Ben Messaoud, A. Tamayol, B. Aliakbarian, H. Y. Zhang, M. Hasan, L. Sánchez-González, E. Arab-Tehrany

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Curcumin has been shown to be effective in many biomedical processes. However, the functionalization of hydrogel constructs with curcumin has been challenging due to its low water solubility. Here, we developed the preparation of alginate/methacrylated gelatin (GelMA) hybrid hydrogels functionalized with nanoliposomes encapsulating curcumin. Physicochemical properties of the polymer solutions and resulting hydrogels were studied. The engineered systems showed great rheological and swelling properties. The release behavior of curcumin-loaded nanoliposomes demonstrated their suitability as a drug delivery system. These novel biomaterial systems could be an excellent candidate for tissue engineering applications.

Original languageEnglish (US)
Pages (from-to)27879-27884
Number of pages6
JournalRSC Advances
Issue number33
StatePublished - 2016
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)


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