TY - JOUR
T1 - Preserving Wideband Tympanometry Information with Artifact Mitigation
AU - Eberhard, Kristine Elisabeth
AU - Ravicz, Michael E.
AU - Merchant, Gabrielle R.
AU - Masud, Salwa F.
AU - Maison, Stéphane F.
AU - Neely, Stephen T.
AU - Nakajima, Hideko Heidi
N1 - Funding Information:
Most importantly, establishing a consensus among researchers and clinicians on identical methodology for making, processing, and presenting measurements will allow data sharing among laboratories and clinical research sites (). Such a data sharing platform has been developed and funded by NIH (). This will enable the development of new and powerful diagnostic methods that require large amounts of data recorded in a similar manner, like machine learning.
Funding Information:
Research reported in this publication was supported for G.R.M. by the National Institute of General Medical Sciences of the National Institutes of Health (NIH) under award number P20GM109023. Support was also provided by National Institute on Deafness and other Communication Disorders (NIDCD) of NIH with grant P50DC015857 (St.F.M.). K.E.E. received PhD fellowship from William Demant Foundation. Funding from J.R.R.’s Gudrun Larsen Eliasen and Nels Kristian Eliason Professorship funding purchased the Interacoustics Titan with the WBT Research Platform.
Publisher Copyright:
© 2022 Lippincott Williams and Wilkins. All rights reserved.
PY - 2022/3/11
Y1 - 2022/3/11
N2 - Objective: Absorbance measured using wideband tympanometry (WBT) has been shown to be sensitive to changes in middle and inner ear mechanics, with potential to diagnose various mechanical ear pathologies. However, artifacts in absorbance due to measurement noise can obscure information related to pathologies and increase intermeasurement variability. Published reports frequently present absorbance that has undergone smoothing to minimize artifact; however, smoothing changes the true absorbance and can destroy important narrow-band characteristics such as peaks and notches at different frequencies. Because these characteristics can be unique to specific pathologies, preserving them is important for diagnostic purposes. Here, we identify the cause of artifacts in absorbance and develop a technique to mitigate artifacts while preserving the underlying WBT information. Design: A newly developed Research Platform for the Interacoustics Titan device allowed us to study raw microphone recordings and corresponding absorbances obtained by WBT measurements. We investigated WBT measurements from normal hearing ears and ears with middle and inner ear pathologies for the presence of artifact and noise. Furthermore, it was used to develop an artifact mitigation procedure and to evaluate its effectiveness in mitigating artifacts without distorting the true WBT information. Results: We observed various types of noise that can plague WBT measurements and that contribute to artifacts in computed absorbances, particularly intermittent low-frequency noise. We developed an artifact mitigation procedure that incorporates a high-pass filter and a Tukey window. This artifact mitigation resolved the artifacts from low-frequency noise while preserving characteristics in absorbance in both normal hearing ears and ears with pathology. Furthermore, the artifact mitigation reduced intermeasurement variability. Conclusions: Unlike smoothing algorithms used in the past, our artifact mitigation specifically removes artifacts caused by noise. It does not change frequency response characteristics, such as narrow-band peaks and notches in absorbance at different frequencies that can be important for diagnosis. Also, by reducing intermeasurement variability, the artifact mitigation can improve the test-retest reliability of these measurements.
AB - Objective: Absorbance measured using wideband tympanometry (WBT) has been shown to be sensitive to changes in middle and inner ear mechanics, with potential to diagnose various mechanical ear pathologies. However, artifacts in absorbance due to measurement noise can obscure information related to pathologies and increase intermeasurement variability. Published reports frequently present absorbance that has undergone smoothing to minimize artifact; however, smoothing changes the true absorbance and can destroy important narrow-band characteristics such as peaks and notches at different frequencies. Because these characteristics can be unique to specific pathologies, preserving them is important for diagnostic purposes. Here, we identify the cause of artifacts in absorbance and develop a technique to mitigate artifacts while preserving the underlying WBT information. Design: A newly developed Research Platform for the Interacoustics Titan device allowed us to study raw microphone recordings and corresponding absorbances obtained by WBT measurements. We investigated WBT measurements from normal hearing ears and ears with middle and inner ear pathologies for the presence of artifact and noise. Furthermore, it was used to develop an artifact mitigation procedure and to evaluate its effectiveness in mitigating artifacts without distorting the true WBT information. Results: We observed various types of noise that can plague WBT measurements and that contribute to artifacts in computed absorbances, particularly intermittent low-frequency noise. We developed an artifact mitigation procedure that incorporates a high-pass filter and a Tukey window. This artifact mitigation resolved the artifacts from low-frequency noise while preserving characteristics in absorbance in both normal hearing ears and ears with pathology. Furthermore, the artifact mitigation reduced intermeasurement variability. Conclusions: Unlike smoothing algorithms used in the past, our artifact mitigation specifically removes artifacts caused by noise. It does not change frequency response characteristics, such as narrow-band peaks and notches in absorbance at different frequencies that can be important for diagnosis. Also, by reducing intermeasurement variability, the artifact mitigation can improve the test-retest reliability of these measurements.
KW - Absorbance
KW - Inner ear mechanics
KW - Middle ear mechanics
KW - Reflectance
KW - Wideband acoustic immittance
KW - Wideband tympanometry
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U2 - 10.1097/AUD.0000000000001117
DO - 10.1097/AUD.0000000000001117
M3 - Article
C2 - 34387582
AN - SCOPUS:85125549722
SN - 0196-0202
VL - 43
SP - 563
EP - 576
JO - Ear and Hearing
JF - Ear and Hearing
IS - 2
ER -