@article{7323d9b0f950449f983bd0f0667bf7d1,
title = "Pressurized Wideband Acoustic Stapedial Reflex Thresholds: Normal Development and Relationships to Auditory Function in Infants",
abstract = "This study analyzed effects of pressurization on wideband acoustic stapedial-muscle reflex (ASR) tests in infants cared for in normal newborn (NN) and neonatal intensive care units (NICU). Effects of hearing-screening outcomes on ASR threshold measurements were also evaluated, and a subsequent longitudinal study established normative threshold ranges over the first year after birth. An initial experiment compared thresholds in newborns measured at ambient pressure in the ear canal and at the tympanometric peak pressure. ASR thresholds for broadband noise were higher for ears that did not pass newborn hearing screening and ASR threshold was 14 dB higher for real-ear compared to coupler conditions. Effects of pressurization were significant for ears that passed screening; thus, ASR testing in infants should be conducted at tympanometric peak pressure. ASR threshold was significantly higher for ears that referred on transient evoked otoacoustic emissions and Auditory Brainstem Response (ABR) screening tests and also for ears with conductive and sensorineural hearing loss diagnosed by ABR. Developmental ASR changes were significant over the first year for both normal and NICU infants. Wideband pressurized ASR thresholds are a clinically relevant measure of newborn hearing screening and diagnostic outcomes.",
keywords = "acoustic stapedial reflex, development, middle ear, middle ear muscle reflexes",
author = "Hunter, {Lisa L.} and Keefe, {Douglas H.} and Feeney, {M. Patrick} and Fitzpatrick, {Denis F.}",
note = "Funding Information: The authors were assisted by John C. Ellison in preliminary analyses of these reflex data. Portions of these results were presented at the Association for Research in Otolaryngology in 2011 and the American Auditory Society in 2014. Research reported in this publication was supported by the National Institute of Deafness and other Communication Disorders of the National Institutes of Health under Award Number R01 DC010202 and an ARRA supplement (DC010202-01S1). Co-author Keefe is involved in commercializing devices to assess middle-ear function in infants. Lisa Hunter has received honoraria from Interacoustics, Inc. and Vivosonic, Inc. for educational lectures. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The content of this article does not represent the views of the Department of Veterans Affairs or of the US Government. Research reported in this publication was supported by the National Institute of Deafness and other Communication Disorders of the National Institutes of Health under Award Number R01 DC010202 and an ARRA supplement (DC010202-01S1). Co-author Keefe is involved in commercializing devices to assess middle-ear function in infants. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The content of this article does not represent the views of the Department of Veterans Affairs or of the United States Government. Publisher Copyright: {\textcopyright} 2016, Association for Research in Otolaryngology.",
year = "2017",
month = feb,
day = "1",
doi = "10.1007/s10162-016-0595-3",
language = "English (US)",
volume = "18",
pages = "49--63",
journal = "JARO - Journal of the Association for Research in Otolaryngology",
issn = "1525-3961",
publisher = "Springer New York",
number = "1",
}