TY - JOUR
T1 - Prevalence and correlates of Kaposi's sarcoma-associated herpesvirus infection in a sample of men who have sex with men in eastern China
AU - Zhang, T.
AU - Lin, H.
AU - Minhas, Veenu
AU - Zhu, W.
AU - Wood, C.
AU - He, N.
PY - 2013/9
Y1 - 2013/9
N2 - This study aimed to determine the seroprevalence of Kaposi's sarcoma-associated herpesvirus (KSHV) and related factors in men who have sex with men (MSM) in China. A total of 208 subjects were recruited from eastern China from 2008 to 2009. Plasma samples were collected and screened for KSHV, HIV and syphilis. Overall, KSHV seroprevalence was 32·7% in the subjects. About 92·7% of subjects reported having ever had anal sex with a man, of whom 67·8% had receptive anal sex and 77·9% had insertive anal sex. About 93·1% of the study participants reported having had oral sex with a man, of whom 76·0% had receptive oral sex and 56·7% had insertive oral sex. KSHV seropositivity was independently associated with receptive anal sex [odds ratio (OR) 2·68, 95% confidence interval (CI) 1·15-6·23], syphilis (OR 3·25, 95% CI 1·56- 6·76) and HSV-2 infection (OR 2·40, 95% CI 1·09- 5·26). KSHV infection is highly prevalent and is probably sexually transmitted among MSM in eastern China.
AB - This study aimed to determine the seroprevalence of Kaposi's sarcoma-associated herpesvirus (KSHV) and related factors in men who have sex with men (MSM) in China. A total of 208 subjects were recruited from eastern China from 2008 to 2009. Plasma samples were collected and screened for KSHV, HIV and syphilis. Overall, KSHV seroprevalence was 32·7% in the subjects. About 92·7% of subjects reported having ever had anal sex with a man, of whom 67·8% had receptive anal sex and 77·9% had insertive anal sex. About 93·1% of the study participants reported having had oral sex with a man, of whom 76·0% had receptive oral sex and 56·7% had insertive oral sex. KSHV seropositivity was independently associated with receptive anal sex [odds ratio (OR) 2·68, 95% confidence interval (CI) 1·15-6·23], syphilis (OR 3·25, 95% CI 1·56- 6·76) and HSV-2 infection (OR 2·40, 95% CI 1·09- 5·26). KSHV infection is highly prevalent and is probably sexually transmitted among MSM in eastern China.
KW - China
KW - Kaposi's sarcoma-associated herpesvirus
KW - men who have sex with men
KW - prevalence
UR - http://www.scopus.com/inward/record.url?scp=84881451787&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84881451787&partnerID=8YFLogxK
U2 - 10.1017/S0950268812002361
DO - 10.1017/S0950268812002361
M3 - Article
C2 - 23114099
AN - SCOPUS:84881451787
SN - 0950-2688
VL - 141
SP - 1823
EP - 1830
JO - Epidemiology and Infection
JF - Epidemiology and Infection
IS - 9
ER -