Abstract
Background Biliopancreatic diversion (BPD) is a form of bariatric surgery that produces substantial and sustained weight loss, improved co-morbidities, and a higher quality of life. However, it does have associated sequelae such as vitamin D deficiency. With limited published data, a comprehensive review of vitamin D levels in BPD patients was warranted. Methods All available 25-hydroxyvitamin D (25-OH-D) levels were assessed from 219 BPD patients. The dates of 25-OH-D levels were compared to each individual patent's surgery date. Data was analyzed according to patient sex, ethnicity, age, and time from surgery. Results The majority (72.3%) of 25-OH-D levels (n=607) in BPD patients were insufficient (≤30 ng/ml), and 46.8% were deficient (≤20 ng/ml). Statistical analysis revealed that 25-OH-D levels decrease over time with BPD patients (n=0.0468), and no significant relationship exists with patient sex, ethnicity, or age. Conclusions This study gives evidence that vitamin D deficiency and insufficiency is prevalent in BPD patients. Despite excess weight loss and oral vitamin D supplementation, the data shows that vitamin D levels continue to decrease over time in BPD patients. Since the current method of vitamin D supplementation is not producing ideal results, other protocol needs to be developed.
Original language | English (US) |
---|---|
Pages (from-to) | 881-884 |
Number of pages | 4 |
Journal | Obesity Surgery |
Volume | 20 |
Issue number | 7 |
DOIs | |
State | Published - Jul 2010 |
Externally published | Yes |
Keywords
- Bariatric surgery
- Biliopancreatic diversion
- Nutrition
- Vitamin D deficiency
- Vitamin D supplementation
- Weight-loss surgery
ASJC Scopus subject areas
- Surgery
- Endocrinology, Diabetes and Metabolism
- Nutrition and Dietetics