Prevention of Vascular Catheter-Related Bloodstream Infections

Mark E. Rupp, Denisa Majorant

Research output: Contribution to journalReview articlepeer-review

18 Scopus citations


Catheter-related bloodstream infections (CRBSI) are responsible for significant morbidity, mortality, and excess health care costs. It is increasingly evident that many CRBSI can be prevented with current knowledge and techniques. Preventive measures can be broadly grouped into clinical practice–based interventions and technologic innovations. Clinical practice–based interventions require changes in human behavior and can be subdivided into interventions before and at the time of insertion and postinsertion. Despite recent successes with prevention of CRBSI, pertinent questions regarding pathogenesis and prevention remain unanswered and work on improved surveillance, devices less prone to infection, and more effective prevention techniques are needed.

Original languageEnglish (US)
Pages (from-to)853-868
Number of pages16
JournalInfectious disease clinics of North America
Issue number4
StatePublished - Dec 1 2016


  • Bacteremia
  • Bloodstream infection
  • Intravascular catheter
  • Prevention

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases


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