TY - JOUR
T1 - Primary central nervous system vasculitis with optic nerve involvement
AU - Benson, Christy E.
AU - Knezevic, Alexander
AU - Lynch, Shannon C.
N1 - Publisher Copyright:
© 2016 by North American Neuro-Ophthalmology Society.
PY - 2016
Y1 - 2016
N2 - A 20-year-old woman presented with headache, decreased vision, eye pain, and urinary retention. During her clinical course, visual acuity declined to 20/800, right eye, and 20/50, left eye, associated with bilateral optic disc edema. Brain magnetic resonance imaging revealed enhancement of the leptomeninges, right optic nerve, and right side of the optic chiasm. Extensive evaluation of the central nervous system (CNS) for an infectious cause was negative. Brain biopsy showed a pattern consistent with vasculitis. The patient was treated with prednisone and cyclophosphamide, resulting in improvement of her vision and systemic symptoms. Primary CNS vasculitis is a rare condition that may affect the anterior visual pathways.
AB - A 20-year-old woman presented with headache, decreased vision, eye pain, and urinary retention. During her clinical course, visual acuity declined to 20/800, right eye, and 20/50, left eye, associated with bilateral optic disc edema. Brain magnetic resonance imaging revealed enhancement of the leptomeninges, right optic nerve, and right side of the optic chiasm. Extensive evaluation of the central nervous system (CNS) for an infectious cause was negative. Brain biopsy showed a pattern consistent with vasculitis. The patient was treated with prednisone and cyclophosphamide, resulting in improvement of her vision and systemic symptoms. Primary CNS vasculitis is a rare condition that may affect the anterior visual pathways.
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U2 - 10.1097/WNO.0000000000000328
DO - 10.1097/WNO.0000000000000328
M3 - Article
C2 - 26693942
AN - SCOPUS:84951309938
SN - 1070-8022
VL - 36
SP - 174
EP - 177
JO - Journal of Neuro-Ophthalmology
JF - Journal of Neuro-Ophthalmology
IS - 2
ER -