Primary follicular lymphoma of the testis in children and adolescents

Mark A. Lones, Martine Raphael, Keith McCarthy, Andrew Wotherspoon, Marie Josee Terrier-Lacombe, Alan D. Ramsay, Ken MacLennan, Mitchell S. Cairo, Mary Gerrard, Jean Michon, Catherine Patte, Ross Pinkerton, Leonard Sender, Anne Auperin, Richard Sposto, Claire Weston, Nyla A. Heerema, Warren G. Sanger, Daniel Von Allmen, Sherrie L. Perkins

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

This study reports 6 cases of primary follicular lymphoma of the testis (PFLT) in children and adolescents correlated with clinical presentation, pathologic features, treatment, and outcome. All 6 patients (age, 3 to 16 y; median, 4 y) had PFLT grade 3 with disease limited to the testis, completely resected and treated with 2 courses of chemotherapy (cyclophosphamide, vincristine, prednisone, doxorubicin). Event-free survival was 100% (follow-up: median, 73 mo; mean, 53 mo; range, 6 to 96 mo). In conclusion, clinical outcome in children and adolescents with PFLT is excellent with treatment including complete surgical resection and 2 courses of cyclophosphamide, vincristine, prednisone, doxorubicin.

Original languageEnglish (US)
Pages (from-to)68-71
Number of pages4
JournalJournal of Pediatric Hematology/Oncology
Volume34
Issue number1
DOIs
StatePublished - Jan 2012

Keywords

  • adolescence
  • child
  • lymphoma B-cell
  • lymphoma follicular
  • testis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

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