Primary Mammary Analog Secretory Carcinoma (MASC) of the Vulva with ETV6-NTRK3 Fusion: A Case Report

Jane K. Nguyen; Julia A. Bridge; Chandrika Joshi; Jesse K. McKenney

doi:10.1097/PGP.0000000000000501

Primary Mammary Analog Secretory Carcinoma (MASC) of the Vulva with ETV6-NTRK3 Fusion: A Case Report

Jane K. Nguyen, Julia A. Bridge, Chandrika Joshi, Jesse K. McKenney

Pathology & Microbiology

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Mammary analog secretory carcinoma is a primary salivary gland neoplasm with histologic, immunophenotypic, and molecular features identical to those of secretory carcinoma of the breast. Similar neoplasms have now been reported to occur in various nonmammary sites including the parotid gland, submandibular gland, sinuses, lip, skin, thyroid gland, and lung. We report, to our knowledge, the first example of a primary vulvar neoplasm with pathologic features identical to secretory carcinoma of the breast and an ETV6-NTRK3 fusion.

Original language	English (US)
Pages (from-to)	283-287
Number of pages	5
Journal	International Journal of Gynecological Pathology
Volume	38
Issue number	3
DOIs	https://doi.org/10.1097/PGP.0000000000000501
State	Published - May 1 2019

Keywords

ETV6
MASC
Mammary analog secretory carcinoma
NTRK3
Vulva

ASJC Scopus subject areas

Pathology and Forensic Medicine
Obstetrics and Gynecology

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10.1097/PGP.0000000000000501

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abstract = "Mammary analog secretory carcinoma is a primary salivary gland neoplasm with histologic, immunophenotypic, and molecular features identical to those of secretory carcinoma of the breast. Similar neoplasms have now been reported to occur in various nonmammary sites including the parotid gland, submandibular gland, sinuses, lip, skin, thyroid gland, and lung. We report, to our knowledge, the first example of a primary vulvar neoplasm with pathologic features identical to secretory carcinoma of the breast and an ETV6-NTRK3 fusion.",

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AU - McKenney, Jesse K.

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N2 - Mammary analog secretory carcinoma is a primary salivary gland neoplasm with histologic, immunophenotypic, and molecular features identical to those of secretory carcinoma of the breast. Similar neoplasms have now been reported to occur in various nonmammary sites including the parotid gland, submandibular gland, sinuses, lip, skin, thyroid gland, and lung. We report, to our knowledge, the first example of a primary vulvar neoplasm with pathologic features identical to secretory carcinoma of the breast and an ETV6-NTRK3 fusion.

AB - Mammary analog secretory carcinoma is a primary salivary gland neoplasm with histologic, immunophenotypic, and molecular features identical to those of secretory carcinoma of the breast. Similar neoplasms have now been reported to occur in various nonmammary sites including the parotid gland, submandibular gland, sinuses, lip, skin, thyroid gland, and lung. We report, to our knowledge, the first example of a primary vulvar neoplasm with pathologic features identical to secretory carcinoma of the breast and an ETV6-NTRK3 fusion.

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Primary Mammary Analog Secretory Carcinoma (MASC) of the Vulva with ETV6-NTRK3 Fusion: A Case Report

Abstract

Keywords

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