Primary melanoma of the sphenoid sinus presenting with a third cranial nerve palsy

Shannon C. Lynch, Andrew G. Lee, Scott M. Graham, Patricia A. Kirby

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

An 83-year-old woman presented with right trigeminal paresthesias, upper lid ptosis, and diplopia and was found to have a right third cranial nerve palsy. MRI disclosed a right sphenocavernous mass with speckled high signal on pre-contrast T1 and correspondingly low signal on T2. Endoscopic sphenoidotomy revealed malignant melanoma. The patient underwent radiation therapy with complete and protracted resolution of the palsy. An extensive evaluation for a primary source was negative. The combination of high T1 signal and low T2 signal in a mass should suggest melanin. An exceedingly rare condition, this is the first English report of its presentation with a third cranial nerve palsy.

Original languageEnglish (US)
Pages (from-to)289-292
Number of pages4
JournalJournal of Neuro-Ophthalmology
Volume25
Issue number4
DOIs
StatePublished - Dec 2005

ASJC Scopus subject areas

  • Ophthalmology
  • Clinical Neurology

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