Abstract
Primary skeletal Ewing's sarcoma that occured in two teenage patients with Down syndrome are reported. Cytogenetic analysis of one of these tumors showed the 11:22 translocation characteristic of Ewing's sarcoma as well as other complex karyotypic changes. The possible role of constitutional trisomy 21 in development of these sarcomas is discussed.
Original language | English (US) |
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Pages (from-to) | 61-68 |
Number of pages | 8 |
Journal | Cancer genetics and cytogenetics |
Volume | 47 |
Issue number | 1 |
DOIs | |
State | Published - Jul 1 1990 |
Externally published | Yes |
ASJC Scopus subject areas
- Molecular Biology
- Genetics
- Cancer Research