TY - JOUR
T1 - Programmed cell death in plants
T2 - Lessons from bacteria?
AU - Wang, Junhui
AU - Bayles, Kenneth W.
N1 - Funding Information:
We thank Dr Muyuan Zhu for insightful discussions regarding the role of AtLrgB in plant cell death, as well as Xu Luo and Kari Nelson for the critical evaluation of this manuscript. This work was supported by the National Natural Science Foundation of China Grant 31170211 (J.W.) and the National Institutes of Health Grants P01-AI83211 (K.W.B.) and R01-AI038901 (K.W.B.).
PY - 2013/3
Y1 - 2013/3
N2 - Programmed cell death (PCD) has well-established roles in the development and physiology of animals, plants, and fungi. Although aspects of PCD control appear evolutionarily conserved between these organisms, the extent of conservation remains controversial. Recently, a putative bacterial PCD protein homolog in plants was found to play a significant role in cell death control, indicating a conservation of function between these highly divergent organisms. Interestingly, these bacterial proteins are thought to be evolutionarily linked to the Bcl-2 family of proteins. In this opinion article, we propose a new unifying model to describe the relationship between bacterial and plant PCD systems and propose that the underlying control of PCD is conserved across at least three Kingdoms of life.
AB - Programmed cell death (PCD) has well-established roles in the development and physiology of animals, plants, and fungi. Although aspects of PCD control appear evolutionarily conserved between these organisms, the extent of conservation remains controversial. Recently, a putative bacterial PCD protein homolog in plants was found to play a significant role in cell death control, indicating a conservation of function between these highly divergent organisms. Interestingly, these bacterial proteins are thought to be evolutionarily linked to the Bcl-2 family of proteins. In this opinion article, we propose a new unifying model to describe the relationship between bacterial and plant PCD systems and propose that the underlying control of PCD is conserved across at least three Kingdoms of life.
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U2 - 10.1016/j.tplants.2012.09.004
DO - 10.1016/j.tplants.2012.09.004
M3 - Review article
C2 - 23083702
AN - SCOPUS:84875239150
SN - 1360-1385
VL - 18
SP - 133
EP - 139
JO - Trends in Plant Science
JF - Trends in Plant Science
IS - 3
ER -