'Prostatic acid phosphatase?'. A comparison of acid phosphatase activities in epithelial cells, granulocytes, monocytes, lymphocytes, and platelets purified by velocity sedimentation in isokinetic gradients of ficoll in tissue culture medium

S. R. Helms, M. G. Brattain, T. G. Pretlow, J. I. Kreisberg

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

Numerous investigators have found several substrates and inhibitors to be particularly suited for the demonstration of acid phosphatase of prostatic origin. There has been much controversy over the specificity or lack of specificity of several substrates and inhibitors. The authors investigated acid phosphatase activities obtained from several kinds of purified cells. None of the substrates or inhibitors studied allowed a discrimination of 'prostatic' acid phosphatase from acid phosphatase activities obtained from other kinds of cells.

Original languageEnglish (US)
Pages (from-to)529-537
Number of pages9
JournalAmerican Journal of Pathology
Volume88
Issue number3
StatePublished - 1977
Externally publishedYes

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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