Abstract
A 72-year-old man presented with a 6-month history of dysphagia, fatigue, 60-lb weight loss, and central nervous system (CNS) deficits. Diffusion-weighted magnetic resonance imaging (MRI) of the brain showed mildly elevated nonrestricted apparent diffusion coefficients in the middle cerebellar peduncles, and magnetic resonance spectroscopy (MRS) showed decreased N-acetylaspartate and creatine with increased choline. Diffusion-weighted MRI and MRS offer non-invasive methods to help evaluate in vivo physiologic changes of CNS involvement in Whipple disease.
Original language | English (US) |
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Pages (from-to) | 320-322 |
Number of pages | 3 |
Journal | Journal of Computer Assisted Tomography |
Volume | 29 |
Issue number | 3 |
DOIs | |
State | Published - 2005 |
Externally published | Yes |
Keywords
- Central nervous system infections
- Diffusion-weighted imaging
- Magnetic resonance spectroscopy
- Whipple disease
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging