Proton MR spectroscopy of Sjogren-Larsson's syndrome

Toshiyuki Mano, Jiro Ono, Tatsuro Kaminaga, Katsumi Imai, Kosuke Sakurai, Koushi Harada, Toshisaburo Nagai, William B. Rizzo, Shintaro Okada

Research output: Contribution to journalArticle

33 Scopus citations


We performed single-voxel proton MR spectroscopy (1H-MRS) in two children with Sjogren-Larsson's syndrome (SLS). Both patients showed two abnormal spectral peaks at 1.3 ppm and 0.9 ppm that were obtained with short echo times. These two abnormal spectral peaks were seen in high-intensity areas on T2-weighted images and also in basal ganglia of normal intensities. 1H-MRS may be useful for establishing the diagnosis and investigating the natural history of SLS, and for evaluating the efficacy of therapeutic approaches to SLS.

Original languageEnglish (US)
Pages (from-to)1671-1673
Number of pages3
JournalAmerican Journal of Neuroradiology
Issue number9
StatePublished - Nov 4 1999

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

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    Mano, T., Ono, J., Kaminaga, T., Imai, K., Sakurai, K., Harada, K., Nagai, T., Rizzo, W. B., & Okada, S. (1999). Proton MR spectroscopy of Sjogren-Larsson's syndrome. American Journal of Neuroradiology, 20(9), 1671-1673.