Purification and partial characterization of two proteinases from Clostridium butyricum M 55

P. Ciborowski, W. Hryniewicz, J. Jeljaszewicz

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Clostridium butyricum M55 proteinases were purified by application of a multistep procedure involving ethanol precipitation, DEAE cellulose chromatography and molecular sieving. The purified enzymes obtained were called proteinase I and proteinase II. They appeared to be homogenous when examined by molecular sieving and Polyacrylamide gel electrophoresis. The highly purified proteinases were studied for their physico-chemical properties. The influences of pH, temperature, ionic strength and amino acids composition were investigated. The effects of metal ions and of protein-structure-modifying agents support views suggesting the character of these enzymes.

Original languageEnglish (US)
Pages (from-to)180-192
Number of pages13
JournalZentralblatt fur Bakteriologie Mikrobiologie und Hygiene - Abt. 1 Orig. A
Volume268
Issue number2
DOIs
StatePublished - 1988
Externally publishedYes

ASJC Scopus subject areas

  • Immunology

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