Pushing the agenda for intravenous push administration in outpatient parenteral antimicrobial therapy

Tanner M. Johnson; Leah C. Whitman Webster; Meera Mehta; Jessica E. Johnson; Nicolás Cortés-Penfield; Christina G. Rivera

doi:10.1177/20499361231193920

Pushing the agenda for intravenous push administration in outpatient parenteral antimicrobial therapy

Tanner M. Johnson, Leah C. Whitman Webster, Meera Mehta, Jessica E. Johnson, Nicolás Cortés-Penfield, Christina G. Rivera

Research output: Contribution to journal › Review article › peer-review

Abstract

Intravenous push (IVP) antimicrobial administration refers to rapid bolus infusion of medication. This drug delivery method offers improved patient convenience, superior patient and nursing satisfaction, and cost savings when used in outpatient parenteral antimicrobial therapy (OPAT). Antimicrobial agents must demonstrate optimal physiochemical and pharmacologic characteristics, as well as sufficient syringe stability, to be administered in this manner. Additionally, impacts on medication tolerability, patient safety, and effectiveness must be considered. This narrative review summarizes the available data and practical implications of IVP administration of antimicrobials in the OPAT setting.

Original language	English (US)
Journal	Therapeutic Advances in Infectious Disease
Volume	10
DOIs	https://doi.org/10.1177/20499361231193920
State	Published - Jan 1 2023

Keywords

OPAT
administration
antibiotics
antimicrobials
infusion
intravenous push

ASJC Scopus subject areas

Infectious Diseases
Pharmacology (medical)

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10.1177/20499361231193920

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title = "Pushing the agenda for intravenous push administration in outpatient parenteral antimicrobial therapy",

abstract = "Intravenous push (IVP) antimicrobial administration refers to rapid bolus infusion of medication. This drug delivery method offers improved patient convenience, superior patient and nursing satisfaction, and cost savings when used in outpatient parenteral antimicrobial therapy (OPAT). Antimicrobial agents must demonstrate optimal physiochemical and pharmacologic characteristics, as well as sufficient syringe stability, to be administered in this manner. Additionally, impacts on medication tolerability, patient safety, and effectiveness must be considered. This narrative review summarizes the available data and practical implications of IVP administration of antimicrobials in the OPAT setting.",

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AU - Johnson, Tanner M.

AU - Whitman Webster, Leah C.

AU - Mehta, Meera

AU - Johnson, Jessica E.

AU - Cortés-Penfield, Nicolás

AU - Rivera, Christina G.

N1 - Publisher Copyright: © The Author(s), 2023.

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N2 - Intravenous push (IVP) antimicrobial administration refers to rapid bolus infusion of medication. This drug delivery method offers improved patient convenience, superior patient and nursing satisfaction, and cost savings when used in outpatient parenteral antimicrobial therapy (OPAT). Antimicrobial agents must demonstrate optimal physiochemical and pharmacologic characteristics, as well as sufficient syringe stability, to be administered in this manner. Additionally, impacts on medication tolerability, patient safety, and effectiveness must be considered. This narrative review summarizes the available data and practical implications of IVP administration of antimicrobials in the OPAT setting.

AB - Intravenous push (IVP) antimicrobial administration refers to rapid bolus infusion of medication. This drug delivery method offers improved patient convenience, superior patient and nursing satisfaction, and cost savings when used in outpatient parenteral antimicrobial therapy (OPAT). Antimicrobial agents must demonstrate optimal physiochemical and pharmacologic characteristics, as well as sufficient syringe stability, to be administered in this manner. Additionally, impacts on medication tolerability, patient safety, and effectiveness must be considered. This narrative review summarizes the available data and practical implications of IVP administration of antimicrobials in the OPAT setting.

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KW - antibiotics

KW - antimicrobials

KW - infusion

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Pushing the agenda for intravenous push administration in outpatient parenteral antimicrobial therapy

Abstract

Keywords

ASJC Scopus subject areas

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