Qualitative and quantitative analyses of resin-bound organic compounds

Mark Irving; Jason Cournoyer; Rongshi Li; Chris Santos; Bing Yan

doi:10.2174/1386207013331066

Qualitative and quantitative analyses of resin-bound organic compounds

Mark Irving, Jason Cournoyer, Rongshi Li, Chris Santos, Bing Yan

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Methods for qualitative and quantitative analyses of resin-bound organic compounds are essential tools for chemistry development in solid-phase combinatorial and parallel syntheses. Here we discuss the use of gel-phase ¹⁹F NMR, the fluoride ion-selective electrode method, and spectrophotometry for monitoring solid-phase reactions. Our results indicate that the application of these diverse methods for analyzing the outcome of solid-phase combinatorial synthesis are sensitive and conclusive.

Original language	English (US)
Pages (from-to)	353-362
Number of pages	10
Journal	Combinatorial Chemistry and High Throughput Screening
Volume	4
Issue number	4
DOIs	https://doi.org/10.2174/1386207013331066
State	Published - 2001
Externally published	Yes

ASJC Scopus subject areas

Drug Discovery
Computer Science Applications
Organic Chemistry

Access to Document

10.2174/1386207013331066

Cite this

@article{883f78dea3f64f488e6e5cdf8d951502,

title = "Qualitative and quantitative analyses of resin-bound organic compounds",

abstract = "Methods for qualitative and quantitative analyses of resin-bound organic compounds are essential tools for chemistry development in solid-phase combinatorial and parallel syntheses. Here we discuss the use of gel-phase 19F NMR, the fluoride ion-selective electrode method, and spectrophotometry for monitoring solid-phase reactions. Our results indicate that the application of these diverse methods for analyzing the outcome of solid-phase combinatorial synthesis are sensitive and conclusive.",

author = "Mark Irving and Jason Cournoyer and Rongshi Li and Chris Santos and Bing Yan",

year = "2001",

doi = "10.2174/1386207013331066",

language = "English (US)",

volume = "4",

pages = "353--362",

journal = "Combinatorial Chemistry and High Throughput Screening",

issn = "1386-2073",

publisher = "Bentham Science Publishers",

number = "4",

}

TY - JOUR

T1 - Qualitative and quantitative analyses of resin-bound organic compounds

AU - Irving, Mark

AU - Cournoyer, Jason

AU - Li, Rongshi

AU - Santos, Chris

AU - Yan, Bing

PY - 2001

Y1 - 2001

N2 - Methods for qualitative and quantitative analyses of resin-bound organic compounds are essential tools for chemistry development in solid-phase combinatorial and parallel syntheses. Here we discuss the use of gel-phase 19F NMR, the fluoride ion-selective electrode method, and spectrophotometry for monitoring solid-phase reactions. Our results indicate that the application of these diverse methods for analyzing the outcome of solid-phase combinatorial synthesis are sensitive and conclusive.

AB - Methods for qualitative and quantitative analyses of resin-bound organic compounds are essential tools for chemistry development in solid-phase combinatorial and parallel syntheses. Here we discuss the use of gel-phase 19F NMR, the fluoride ion-selective electrode method, and spectrophotometry for monitoring solid-phase reactions. Our results indicate that the application of these diverse methods for analyzing the outcome of solid-phase combinatorial synthesis are sensitive and conclusive.

UR - http://www.scopus.com/inward/record.url?scp=0034968522&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034968522&partnerID=8YFLogxK

U2 - 10.2174/1386207013331066

DO - 10.2174/1386207013331066

M3 - Article

C2 - 11472224

AN - SCOPUS:0034968522

SN - 1386-2073

VL - 4

SP - 353

EP - 362

JO - Combinatorial Chemistry and High Throughput Screening

JF - Combinatorial Chemistry and High Throughput Screening

IS - 4

ER -

Qualitative and quantitative analyses of resin-bound organic compounds

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this