Raine syndrome is a lethal, osteosclerotic bone dysplasia. There is a generalized increase in bone density, but the increased ossification in the skull results in a unique "fish-like" appearance to the face. Specific characteristics include a prominent forehead, exophthalmos, midfacial hypoplasia with hypoplastic nose, triangular-shaped mouth, and gum hyperplasia. Fewer than 20 cases have been reported in the literature with survival times varying from minutes to weeks. A retrospective review of the sonographic findings in the presented case documents the unique facial phenotype associated with this rare syndrome.
- Craniofacial dysplasia
- Raine syndrome
ASJC Scopus subject areas
- Radiological and Ultrasound Technology
- Radiology Nuclear Medicine and imaging