Raltegravir-associated Drug-Reaction with Eosinophilia and Systemic Symptoms Syndrome in a Pediatric Patient without Characteristic Human Leukocyte Antigen B∗57:01 or B∗53:01 alleles

Sanya J. Thomas, Jacob T. Kilgore, Bradford A. Becken, Coleen K. Cunningham, Amelia B. Thompson

Research output: Contribution to journalArticlepeer-review

Abstract

We present the first published case of raltegravir-associated drug-reaction with eosinophilia and systemic symptoms (DRESS) syndrome in a child without characteristic human leukocyte antigen haplotypes HLA-B∗57:01 or HLA-B∗53:01. A 4-year-old African American female with perinatally acquired human immunodeficiency virus infection was hospitalized for DRESS after starting a raltegravir-based antiretroviral regimen.

Original languageEnglish (US)
Pages (from-to)363-366
Number of pages4
JournalJournal of the Pediatric Infectious Diseases Society
Volume10
Issue number3
DOIs
StatePublished - Mar 1 2021
Externally publishedYes

Keywords

  • antiretroviral therapy
  • drug-reaction with eosinophilia and systemic symptoms syndrome
  • human immunodeficiency virus
  • human leukocyte antigen-B alleles
  • raltegravir

ASJC Scopus subject areas

  • General Medicine

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