Rapid calcification of the bovine pericardial valve in adolescence: Critical aortic stenosis, hemolytic anemia, and quantitative renal hemosiderosis

S. J. Radio, S. D. Suvalsky, P. J. Hofschire, W. H. Fleming, W. C. Rogler, B. M. McManus

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

A 16-year-old boy developed marked calcific stenosis of an Ionescu-Shiley valve that was implanted in the aortic position 42 months before his sudden death. Renal hemosiderosis caused by intravascular hemolysis was quantitated by atomic absorption spectrophotometry. The accelerated calcification of the bovine pericardial valve in our patient supports the view that, in general, xenografts should not be used in adolescents. Frequent follow-up evaluations are imperative in young patients who receive these valves to avoid the irrevocable progression of valvular stenosis and hemolytic anemia.

Original languageEnglish (US)
Pages (from-to)1118-1121
Number of pages4
JournalArchives of Pathology and Laboratory Medicine
Volume109
Issue number12
StatePublished - 1985

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

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