Abstract
How research during a public health emergency is conducted is recognized as essential to the public health response to that emergency. Such research needs to undergo substantive and meaningful ethical review in a timely manner. Rapid ethical review may be accomplished through a number of mechanisms, including use of local rapid-response institutional review boards (IRBs). We describe use of such a model in the setting of the 2014 Ebola virus disease epidemic and the Rapid-Response IRB's subsequent transition to a multisite single IRB model during the current Covid-19 pandemic. The rapid-response review model is characterized by a small IRB with extensive use of alternate members with specific expertise and by close collaboration with the investigator in an iterative process.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 16-21 |
| Number of pages | 6 |
| Journal | Ethics and Human Research |
| Volume | 46 |
| Issue number | 2 |
| DOIs | |
| State | Published - Mar 1 2024 |
Keywords
- Ebola
- human subjects research
- institutional review board (IRB)
- local rapid-response institutional review board
- public health emergency
- single IRB (sIRB)
ASJC Scopus subject areas
- Health(social science)