Rapid, sequence specific, reusable electronic DNA sensor in microfluidic devices

E. Pavlovic, R. Y. Lai, B. Ferguson, J. S. Swensen, T. T. Wu, R. Sun, A. J. Heeger, K. W. Plaxco, H. T. Soh

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We present an integrated E-Array chip for multi-target, electrochemical detection of DNA which is sensitive, specific, reagentless, reusable and selective enough to use directly in blood serum, soil and other complex media. The self-enclosed device allows in situ cleaning and preparation of the electrodes as well as probing for specific DNA sequences. Detection of DNA amplicons from the H1N1 Human influenza virus was performed at a concentration of 400 nM. Signal uniformity across the three pixel electrode array inside the chamber is discussed.

Original languageEnglish (US)
Title of host publicationProceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
EditorsJean-Louis Viovy, Patrick Tabeling, Stephanie Descroix, Laurent Malaquin
PublisherChemical and Biological Microsystems Society
Pages1680-1682
Number of pages3
ISBN (Electronic)9780979806407
StatePublished - 2007
Externally publishedYes
Event11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 - Paris, France
Duration: Oct 7 2007Oct 11 2007

Publication series

NameProceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007

Conference

Conference11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
Country/TerritoryFrance
CityParis
Period10/7/0710/11/07

Keywords

  • Biosensor
  • DNA sensor
  • Electrochemistry
  • Microfluidics

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

Fingerprint

Dive into the research topics of 'Rapid, sequence specific, reusable electronic DNA sensor in microfluidic devices'. Together they form a unique fingerprint.

Cite this