Rare Cutaneous Malignancies in Skin of Color

Daniel Mosallaei, Erica B. Lee, Marissa Lobl, Dillon Clarey, Ashley Wysong

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


BACKGROUNDThere is a scarcity of information regarding the clinical characteristics of rare cutaneous malignancies in skin of color that has yet to be comprehensively explored.OBJECTIVETo review and compile the racial differences in epidemiology, clinical presentation, histology, treatments, and outcomes of 3 rare skin cancers: dermatofibrosarcoma protuberans (DFSP), Merkel cell carcinoma (MCC), and sebaceous carcinoma (SC).METHODSSeveral searches with keywords denoting specific skin cancer type and race were conducted on PubMed to complete this narrative review.RESULTSWe analyzed 50 sources that were relevant to the initial objective.CONCLUSIONThe literature demonstrates that there are nuances in DFSP, MCC, and SC unique to African Americans, Asians/Pacific Islanders, and Hispanics that may differ significantly from Caucasian counterparts. African Americans consistently suffer from the worst clinical outcomes in all 3 rare cutaneous malignancies reviewed. Greater physician awareness and knowledge of the discussed racial differences is the preliminary step to address these disparities.

Original languageEnglish (US)
Pages (from-to)606-612
Number of pages7
JournalDermatologic Surgery
Issue number6
StatePublished - Jun 1 2022

ASJC Scopus subject areas

  • Surgery
  • Dermatology


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