Rat jugular catheter model of biofilm-mediated infection

Carolyn R. Schaeffer, Keith M. Woods, G. Matthew Longo

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations


Staphylococcus epidermidis is now recognized as the primary cause of nosocomial catheter-mediated infections. Bacteria may be introduced exogenously via contamination of the catheter hub or insertion site and endogenously from sepsis. The in vivo model described in this chapter examines the infection resulting from hematogenous seeding of jugular vein catheters.

Original languageEnglish (US)
Title of host publicationStaphylococcus Epidermidis
Subtitle of host publicationMethods and Protocols
PublisherHumana Press Inc.
Number of pages8
ISBN (Print)9781627037358
StatePublished - 2014

Publication series

NameMethods in Molecular Biology
ISSN (Print)1064-3745


  • Biofilm
  • Central venous catheter (CVC)
  • Cyclophosphamide (CP)
  • Jugular vein
  • Rat model
  • Staphylococcus epidermidis

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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