Reactive oxygen species as transducers of sphinganine-mediated cell death pathway

Mariana Saucedo-García, Ariadna González-Solís, Priscila Rodríguez-Mejía, Teresa de Jesús Olivera-Flores, Sonia Vázquez-Santana, Edgar B. Cahoon, Marina Gavilanes-Ruiz

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Long chain bases or sphingoid bases are building blocks of complex sphingolipids that display a signaling role in programmed cell death in plants. So far, the type of programmed cell death in which these signaling lipids have been demonstrated to participate is the cell death that occurs in plant immunity, known as the hypersensitive response. The few links that have been described in this pathway are: MPK6 activation, increased calcium concentrations and reactive oxygen species (ROS) generation. The latter constitute one of the more elusive loops because of the chemical nature of ROS, the multiple possible cell sites where they can be formed and the ways in which they influence cell structure and function.

Original languageEnglish (US)
Pages (from-to)1616-1619
Number of pages4
JournalPlant Signaling and Behavior
Issue number10
StatePublished - Oct 2011
Externally publishedYes


  • Hydrogen peroxide
  • Long chain bases
  • Programmed cell death
  • Reactive oxygen species
  • Sphinganine
  • Sphingoid bases
  • Superoxide

ASJC Scopus subject areas

  • Plant Science


Dive into the research topics of 'Reactive oxygen species as transducers of sphinganine-mediated cell death pathway'. Together they form a unique fingerprint.

Cite this