Recent advances in electrospun nanofibers for wound healing

Shixuan Chen, Bing Liu, Mark A. Carlson, Adrian F. Gombart, Debra A. Reilly, Jingwei Xie

Research output: Contribution to journalReview articlepeer-review

106 Scopus citations

Abstract

Electrospun nanofibers represent a novel class of materials that show great potential in many biomedical applications including biosensing, regenerative medicine, tissue engineering, drug delivery and wound healing. In this work, we review recent advances in electrospun nanofibers for wound healing. This article begins with a brief introduction on the wound, and then discusses the unique features of electrospun nanofibers critical for wound healing. It further highlights recent studies that have used electrospun nanofibers for wound healing applications and devices, including sutures, multifunctional dressings, dermal substitutes, engineered epidermis and fullthickness skin regeneration. Finally, we finish with conclusions and future perspective in this field.

Original languageEnglish (US)
Pages (from-to)1335-1352
Number of pages18
JournalNanomedicine
Volume12
Issue number11
DOIs
StatePublished - Jun 2017

Keywords

  • Electrospun nanofibers
  • Local drug delivery
  • Scaffold
  • Skin regeneration
  • Wound healing

ASJC Scopus subject areas

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomedical Engineering
  • Materials Science(all)

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