Reclassifying pseudopolyps in inflammatory bowel disease: Histologic and endoscopic description in the new era of mucosal healing

Mona Rezapour, Maria Alejandra Quintero, Nidah S. Khakoo, Daniel A. Sussman, Jodie A. Barkin, Jennifer Clarke, Tanya Varma, Amar R. Deshpande, David H. Kerman, Oriana Damas, Maria T. Abreu

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction: In this study, we identify the frequency of pseudopolyps (PPs) with normal histology and their association to surrounding tissue. Methods: Patients were enrolled in a study identifying endoscopic characteristics of PPs (n = 29) or were collected as part of our IBD biobank (n = 16). Statistical analysis included Stata v.15.0. chi-square and Student t-test. Results: A total of 45 patients with 117 PP biopsies were identified. More patients with healed PP were in endoscopic remission compared with those with inflammatory PP (82.6% vs 17.4%, respectively). Conclusion: This is the first study to find mucosal healing of PPs and its association with deep remission.

Original languageEnglish (US)
JournalCrohn's and Colitis 360
Volume1
Issue number3
DOIs
StatePublished - Oct 1 2019

Keywords

  • Healed pseudopolyps
  • Inflammatory bowel disease
  • Inflammatory pseudopolyps

ASJC Scopus subject areas

  • Gastroenterology

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