Abstract
The recognition of DNA tertiary structure is observed by the synthetic polycation. This is unprecedented for polyelectrolyte complexes of DNA. To increase stability of the complexes in aqueous dispersions, block and graft copolymers containing polycation and nonionic water-soluble polymer chains are developed. Binding of these copolymers with DNA chains results in formation of species containing hydrophobic regions from neutralized DNA and polycation. By changing composition of the complex and polycation structure, one can vary physicochemical properties and optimize biological activity of the complexes.
| Original language | English (US) |
|---|---|
| Title of host publication | American Chemical Society, Polymer Preprints, Division of Polymer Chemistry |
| Publisher | ACS |
| Pages | 1006-1007 |
| Number of pages | 2 |
| Volume | 41 |
| Edition | 1 |
| State | Published - Mar 2000 |
| Event | The San Francisco Meeting - San Francisco, CA, USA Duration: Mar 26 2000 → Mar 31 2000 |
Other
| Other | The San Francisco Meeting |
|---|---|
| City | San Francisco, CA, USA |
| Period | 3/26/00 → 3/31/00 |
ASJC Scopus subject areas
- Polymers and Plastics