Rectal cancer, version 6.2020: Featured updates to the NCCN guidelines

Al B. Benson, Alan P. Venook, Mahmoud M. Al-Hawary, Mustafa A. Arain, Yi Jen Chen, Kristen K. Ciombor, Stacey Cohen, Harry S. Cooper, Dustin Deming, Ignacio Garrido-Laguna, Jean L. Grem, Andrew Gunn, Sarah Hoffe, Joleen Hubbard, Steven Hunt, Natalie Kirilcuk, Smitha Krishnamurthi, Wells A. Messersmith, Jeffrey Meyerhardt, Eric D. MillerMary F. Mulcahy, Steven Nurkin, Michael J. Overman, Aparna Parikh, Hitendra Patel, Katrina Pedersen, Leonard Saltz, Charles Schneider, David Shibata, John M. Skibber, Constantinos T. Sofocleous, Elena M. Stoffel, Eden Stotsky-Himelfarb, Christopher G. Willett, Alyse Johnson-Chilla, Lisa A. Gurski

Research output: Contribution to journalReview article

1 Scopus citations

Abstract

The NCCN Guidelines for Rectal Cancer provide recommendations for the diagnosis, evaluation, treatment, and follow-up of patients with rectal cancer. These NCCN Guidelines Insights summarize the panel discussion behind recent important updates to the guidelines. These updates include clarifying the definition of rectum and differentiating the rectumfromthe sigmoid colon; the total neoadjuvant therapy approach for localized rectal cancer; and biomarker-targeted therapy for metastatic colorectal cancer, with a focus on new treatment options for patients with BRAF V600E- or HER2 amplification- positive disease.

Original languageEnglish (US)
Pages (from-to)807-815
Number of pages9
JournalJNCCN Journal of the National Comprehensive Cancer Network
Volume18
Issue number7
DOIs
StatePublished - Jul 2020

ASJC Scopus subject areas

  • Oncology

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    Benson, A. B., Venook, A. P., Al-Hawary, M. M., Arain, M. A., Chen, Y. J., Ciombor, K. K., Cohen, S., Cooper, H. S., Deming, D., Garrido-Laguna, I., Grem, J. L., Gunn, A., Hoffe, S., Hubbard, J., Hunt, S., Kirilcuk, N., Krishnamurthi, S., Messersmith, W. A., Meyerhardt, J., ... Gurski, L. A. (2020). Rectal cancer, version 6.2020: Featured updates to the NCCN guidelines. JNCCN Journal of the National Comprehensive Cancer Network, 18(7), 807-815. https://doi.org/10.6004/jnccn.2020.0032