TY - JOUR
T1 - Recurrent EGFR-mutated non-small cell lung cancer discovered by abnormal mammogram
T2 - Adjuvant/frontline metastatic management options
AU - Copur, Mehmet Sitki
AU - Lackner, Rudy
AU - Rodriguez, Paul
AU - Horn, Adam J.
AU - Faris, Shellie
AU - Zusag, Thomas
N1 - Publisher Copyright:
© 2020 UBM Medica Healthcare Publications. All rights reserved.
PY - 2020
Y1 - 2020
N2 - Breast metastasis from extramammary malignancy is rare, with a reported incidence rate of 0.4% to 1.3% in the published literature. The primary malignancies that most commonly metastasize to the breast are leukemia, lymphoma, and malignant melanoma. Here, we report a very rare case of metastatic EGFR-mutated non-small cell lung cancer (NSCLC) in the breast detected by screening mammography. The patient had initially been diagnosed with a clinical stage IIIA NSCLC and had been treated with neoadjuvant chemoradiation followed by curative-intent surgery. Several interesting aspects of the case, along with a discussion of evolving adjuvant and frontline metastatic management options in EGFR-mutated NSCLC, will be presented.
AB - Breast metastasis from extramammary malignancy is rare, with a reported incidence rate of 0.4% to 1.3% in the published literature. The primary malignancies that most commonly metastasize to the breast are leukemia, lymphoma, and malignant melanoma. Here, we report a very rare case of metastatic EGFR-mutated non-small cell lung cancer (NSCLC) in the breast detected by screening mammography. The patient had initially been diagnosed with a clinical stage IIIA NSCLC and had been treated with neoadjuvant chemoradiation followed by curative-intent surgery. Several interesting aspects of the case, along with a discussion of evolving adjuvant and frontline metastatic management options in EGFR-mutated NSCLC, will be presented.
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U2 - 10.46883/ONC.2020.3409.0347
DO - 10.46883/ONC.2020.3409.0347
M3 - Article
C2 - 32965664
AN - SCOPUS:85091597941
SN - 0890-9091
SP - 347
EP - 351
JO - Oncology (United States)
JF - Oncology (United States)
IS - 3409
ER -