TY - JOUR
T1 - Recurrent orbital inflammation from metastatic orbital carcinoid tumor
AU - Knox, Robert J.
AU - Gigantelli, James W.
AU - Arthurs, Bryan P.
PY - 2001
Y1 - 2001
N2 - Purpose: To report an unusual clinical presentation for carcinoid tumor metastatic to the orbit. Methods: Two adult patients with metastatic carcinoid tumor and unilateral orbital masses are described. Results: Both patients sought treatment for acute unilateral orbital inflammation. Neuroimaging revealed orbital metastases adjacent to the inflamed adnexal tissue. Based on each patient's description of similar, prior, untreated episodes, minimal medical management was initiated. Resolution of the inflammatory signs was spontaneous in one case and assisted by pulsed, systemic corticosteroids in the second case. Compressive neuropathic vision loss occurred 11 months later in the second case. Conclusions: Carcinoid tumor metastatic to the orbit may manifest as recurrent orbital and ocular adnexal inflammation. These signs differ from systemic carcinoid syndrome in that they are unilateral, limited lo only the orbital and ocular adnexal soft tissues, and resolve over days. Clinicians must carefully differentiate this manifestation from that of tumor necrosis, adnexal infection, or orbital outlet obstruction. This presentation may result from the spontaneous release of local inflammatory mediators intrinsic lo the orbital tumor.
AB - Purpose: To report an unusual clinical presentation for carcinoid tumor metastatic to the orbit. Methods: Two adult patients with metastatic carcinoid tumor and unilateral orbital masses are described. Results: Both patients sought treatment for acute unilateral orbital inflammation. Neuroimaging revealed orbital metastases adjacent to the inflamed adnexal tissue. Based on each patient's description of similar, prior, untreated episodes, minimal medical management was initiated. Resolution of the inflammatory signs was spontaneous in one case and assisted by pulsed, systemic corticosteroids in the second case. Compressive neuropathic vision loss occurred 11 months later in the second case. Conclusions: Carcinoid tumor metastatic to the orbit may manifest as recurrent orbital and ocular adnexal inflammation. These signs differ from systemic carcinoid syndrome in that they are unilateral, limited lo only the orbital and ocular adnexal soft tissues, and resolve over days. Clinicians must carefully differentiate this manifestation from that of tumor necrosis, adnexal infection, or orbital outlet obstruction. This presentation may result from the spontaneous release of local inflammatory mediators intrinsic lo the orbital tumor.
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U2 - 10.1097/00002341-200103000-00013
DO - 10.1097/00002341-200103000-00013
M3 - Article
C2 - 11281589
AN - SCOPUS:0035104416
VL - 17
SP - 137
EP - 139
JO - Ophthalmic Plastic and Reconstructive Surgery
JF - Ophthalmic Plastic and Reconstructive Surgery
SN - 0740-9303
IS - 2
ER -