Regio- and diastereoselective boron-mediated aldol reactions of chiral α,β,γ,δ-unsaturated N-acyloxazolidinones

James M. Takacs, Mohamad R. Jaber, Benjamin J. Swanson, Steven J. Mehrman

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Chiral N-acyloxazolidinones derived from conjugated dienoic acids undergo boron-mediated aldol condensation in good yield and with high regio- and diastereoselectivity to provide a convenient method for introducing a 1,3-diene subunit. The condensation of a homologous triene derivative is also described.

Original languageEnglish (US)
Pages (from-to)4313-4324
Number of pages12
JournalTetrahedron Asymmetry
Volume9
Issue number24
DOIs
StatePublished - Dec 24 1998

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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