Regional assignment of human tissue factor gene (F3) to chromosome 1p21-p22

Fa Ten Kao; Judith Hartz; Renata Horton; Yale Nemerson; Steven D. Carson

doi:10.1007/BF01534649

Regional assignment of human tissue factor gene (F3) to chromosome 1p21-p22

Fa Ten Kao, Judith Hartz, Renata Horton, Yale Nemerson, Steven D. Carson

Pathology & Microbiology

Research output: Contribution to journal › Article

13 Scopus citations

Abstract

Tissue factor, or coagulation factor III, is a membrane-bound glycoprotein and acts as a cofactor for factor VII-dependent initiation of blood coagulation. The tissue factor gene (F3) was previously assigned to human chromosome 1, region p21-pter. The present report has further refined the mapping position to 1p21-p22 using a cDNA probe for the tissue factor gene and in situ hybridization to metaphase chromosomes.

Original language	English (US)
Pages (from-to)	407-410
Number of pages	4
Journal	Somatic Cell and Molecular Genetics
Volume	14
Issue number	4
DOIs	https://doi.org/10.1007/BF01534649
State	Published - Jul 1988

ASJC Scopus subject areas

Genetics
Cell Biology

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Kao, F. T., Hartz, J., Horton, R., Nemerson, Y., & Carson, S. D. (1988). Regional assignment of human tissue factor gene (F3) to chromosome 1p21-p22. Somatic Cell and Molecular Genetics, 14(4), 407-410. https://doi.org/10.1007/BF01534649

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abstract = "Tissue factor, or coagulation factor III, is a membrane-bound glycoprotein and acts as a cofactor for factor VII-dependent initiation of blood coagulation. The tissue factor gene (F3) was previously assigned to human chromosome 1, region p21-pter. The present report has further refined the mapping position to 1p21-p22 using a cDNA probe for the tissue factor gene and in situ hybridization to metaphase chromosomes.",

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AU - Kao, Fa Ten

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AU - Carson, Steven D.

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AB - Tissue factor, or coagulation factor III, is a membrane-bound glycoprotein and acts as a cofactor for factor VII-dependent initiation of blood coagulation. The tissue factor gene (F3) was previously assigned to human chromosome 1, region p21-pter. The present report has further refined the mapping position to 1p21-p22 using a cDNA probe for the tissue factor gene and in situ hybridization to metaphase chromosomes.

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