Regional assignment of human tissue factor gene (F3) to chromosome 1p21-p22

Fa Ten Kao, Judith Hartz, Renata Horton, Yale Nemerson, Steven D. Carson

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Tissue factor, or coagulation factor III, is a membrane-bound glycoprotein and acts as a cofactor for factor VII-dependent initiation of blood coagulation. The tissue factor gene (F3) was previously assigned to human chromosome 1, region p21-pter. The present report has further refined the mapping position to 1p21-p22 using a cDNA probe for the tissue factor gene and in situ hybridization to metaphase chromosomes.

Original languageEnglish (US)
Pages (from-to)407-410
Number of pages4
JournalSomatic Cell and Molecular Genetics
Volume14
Issue number4
DOIs
StatePublished - Jul 1 1988

ASJC Scopus subject areas

  • Genetics
  • Cell Biology

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