Relation of Neurological Soft Signs to Nonverbal Memory Performance in Obsessive-Compulsive Disorder

David Mataix-Cols, Pino Alonso, Rosa Hernández, Thilo Deckersbach, Cary R. Savage, José Manuel Menchón, Julio Vallejo

Research output: Contribution to journalArticlepeer-review

44 Scopus citations


Few studies have examined the relation between neurological soft signs (NSS) and neuropsychological performance in Obsessive-Compulsive Disorder (OCD). Thirty outpatients with primary OCD and 30 matched normal controls were administered the Cambridge Neurological Inventory and the Rey-Osterrieth Complex Figure Test (RCFT). A series of multiple regression models tested the relationship between NSS and performance on the RCFT. Patients presented significantly more neurological soft signs than controls on both sides of the body, and were impaired on the free recall and organization scores of the RCFT. Nonverbal memory deficits in OCD were predicted independently by organizational strategies during the copy condition of the RCFT, and neurological soft signs. There might be at least two variables independently mediating nonverbal memory deficits in OCD: (1) a cognitive organization and planning component, and (2) a complex motor regulatory component.

Original languageEnglish (US)
Pages (from-to)842-851
Number of pages10
JournalJournal of Clinical and Experimental Neuropsychology
Issue number6
StatePublished - Sep 2003
Externally publishedYes

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Clinical Psychology
  • Neurology
  • Clinical Neurology


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