Relationship of menstrual cycle and vaginal infection in female rhesus macaques challenged with repeated, low doses of SIVmac251

Monica R. Morris, Siddappa N. Byrareddy, Francois Villinger, Tara C. Henning, Katherine Butler, Aftab A. Ansari, Janet M. McNicholl, Ellen N. Kersh

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

Varying susceptibility during menstrual cycling could be a factor for S(H)IV infection risk in female rhesus macaques. We retrospectively determined vaginal SIV infection time points relative to the menstrual cycle in a group of rhesus macaques (n=11) enrolled in an HIV transmission trial. Eight of nine rhesus macaques became infected around menstruation time.

Original languageEnglish (US)
Pages (from-to)301-305
Number of pages5
JournalJournal of medical primatology
Volume44
Issue number5
DOIs
StatePublished - Oct 1 2015
Externally publishedYes

Keywords

  • Menstrual cycle
  • Progesterone
  • Rhesus macaque
  • SIV

ASJC Scopus subject areas

  • Animal Science and Zoology
  • General Veterinary

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