TY - JOUR
T1 - Release by ethanol of vitamins into rat liver perfusates
AU - Sorrell, M. F.
AU - Baker, H.
AU - Barak, A. J.
AU - Frank, O.
PY - 1974
Y1 - 1974
N2 - In vitro perfusion of rat liver with ethanol (EtOH) causes a release of all vitamins from the liver stores, except biotin, vitamins A, E, C, and β carotene. The concentration of vitamins released from the liver by EtOH in decreasing order was B12 > B6 > pantothenate > thiamin > riboflavin > nicotinate > folate. The B12 concentration in the EtOH perfusate was high when compared with the perfusate without EtOH, implying that B12 can be rapidly released from a liver exposed to EtOH. Results also suggest that when a liver exposed to EtOH releases a vitamin from its stores, it cannot rebind the released vitamin while EtOH is being recirculated.
AB - In vitro perfusion of rat liver with ethanol (EtOH) causes a release of all vitamins from the liver stores, except biotin, vitamins A, E, C, and β carotene. The concentration of vitamins released from the liver by EtOH in decreasing order was B12 > B6 > pantothenate > thiamin > riboflavin > nicotinate > folate. The B12 concentration in the EtOH perfusate was high when compared with the perfusate without EtOH, implying that B12 can be rapidly released from a liver exposed to EtOH. Results also suggest that when a liver exposed to EtOH releases a vitamin from its stores, it cannot rebind the released vitamin while EtOH is being recirculated.
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U2 - 10.1093/ajcn/27.7.743
DO - 10.1093/ajcn/27.7.743
M3 - Article
C2 - 4417898
AN - SCOPUS:0016168424
SN - 0002-9165
VL - 27
SP - 743
EP - 745
JO - American Journal of Clinical Nutrition
JF - American Journal of Clinical Nutrition
IS - 7
ER -