Release of calcium from inositol 1,4,5-trisphosphate receptor-regulated stores by HIV-1 Tat regulates TNF-α production in human macrophages

Keyphrases

• HIV-1 Tat 100%
• Macrophages 100%
• Human Macrophages 100%
• Intracellular Calcium 100%
• Inositol 1,4,5-trisphosphate Receptor (IP3R) 100%
• Xestospongin C 66%
• HIV-associated Dementia 33%
• Protein Kinase 33%
• Microglia 33%
• Pertussis Toxin 33%
• Phospholipase C 33%
• Astrocytes 33%
• PKC Isoforms 33%
• Neuropathogenesis 33%
• Viral Glycoprotein 33%
• Protein Kinase C Inhibitor 33%
• Inositol 1,4,5-trisphosphate 33%
• U73122 33%
• Intracellular Activation 33%
• IP3 Receptor 33%
• BAPTA-AM 33%
• Phospholipase A2 Inhibitor 33%
• Primary Macrophages 33%
• Intracellular Stores 33%
• Calcium Stores 33%
• Cytopathic 33%

Biochemistry, Genetics and Molecular Biology

• Macrophage 100%
• Human Immunodeficiency Virus 1 100%
• Tumor Necrosis Factor 100%
• Inositol 1,4,5 Trisphosphate Receptor 100%
• Calcium Cell Level 50%
• Isoform 16%
• Human Immunodeficiency Virus 16%
• Eicosanoid Receptor 16%
• Microglia 16%
• Protein Kinase C 16%
• Cytokine 16%
• Astrocyte 16%
• Herpes Simplex Virus Protein Vmw65 16%
• Protein Kinase A 16%
• Inositol 16%
• Phospholipase C 16%
• Pertussis Toxin 16%
• Phospholipase A2 16%
• Calcium Transport 16%

Neuroscience

• Human Immunodeficiency Virus 100%
• Macrophage 100%
• Inositol 1,4,5 Trisphosphate Receptor 100%
• HIV Associated Dementia 20%
• Eicosanoid Receptor 20%
• Microglia 20%
• Protein Kinase C 20%
• Calcium Transport 20%
• Astrocyte 20%
• Herpes Simplex Virus Protein Vmw65 20%
• Pertussis Toxin 20%
• Protein Kinase A 20%
• Inositol 1,4,5 Trisphosphate 20%
• Phospholipase C 20%
• Phospholipase A2 20%