Reproducibility of wavefront measurements using the LADARWave aberrometer

Craig D. Lewis, Ronald R. Krueger

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


PURPOSE: To test reproducibility of lower and higher order aberration measurements using the Alcon LADARWave system. METHODS: Measurements were obtained using the LADARWave aberrometer from 100 eyes (50 patients) who presented for refractive surgery. Each patient underwent 2 separate examinations a minimum of 1 day apart. Zernike polynomial values for these 2 separate measurements were recorded based on a calculated pupil size of 6.5 mm; reproducibility was assessed by analyzing the mean difference between the 2 measurements. RESULTS: The mean difference for defocus was 0.17±0.12 μm, which represented 2.6%±1.9% of the mean defocus value (6.33 μm). The mean difference for astigmatism was 0.11±0.12 μm, which represented 23%±26% of the mean astigmatism value (0.45 μm). The mean difference for coma was 0.06±0.06 μm, which represented 37%±37% of the mean coma value (0.16 μm). The mean difference for spherical aberration was 0.04±0.04 μm, which represented 18%±18% of the mean spherical aberration value (0.22 μm). CONCLUSIONS: Measurements for defocus were reproducible whereas measurements of astigmatism and higher order aberrations were more variable. The absolute root-mean-square differences between measurements were small, despite the many possible sources of error and variability. Surgical outcomes suggest that the LADARWave aberrometer is measuring at an appropriate clinteat resolution.

Original languageEnglish (US)
Pages (from-to)S973-S979
JournalJournal of Refractive Surgery
Issue number9
StatePublished - Nov 2006
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology


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