Resistance of viruses to antiviral drugs

A. G. Freifeld, J. M. Ostrove

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations


In recent years, substantial advances in antiviral therapy have been made; however, in the immunocompromised host, antiviral drug resistance is becoming an issue of increasing clinical importance. Understanding the mechanism of action of antiviral agents, especially those used to treat herpesvirus infections, may enable us to design new therapeutic agents and better treatment regimens to deal with antiviral drug resistance.

Original languageEnglish (US)
Pages (from-to)247-259
Number of pages13
JournalAnnual Review of Medicine
StatePublished - 1991
Externally publishedYes


  • Cytomegalovirus
  • Herpes simplex virus
  • Varicella zoster virus

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology


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