@article{b1c86ccbf396461b87b238175cceb16d,
title = " Response to Fungal Dysbiosis by Gut-Resident CX3CR1 + Mononuclear Phagocytes Aggravates Allergic Airway Disease ",
abstract = "How mycobiota influence immunity in gut distal sites is not well understood. Li et al. developed protocols for gut-targeted depletion of phagocytes and mycobiota-free mice to investigate the influence of fungi on gut-lung crosstalk. They reveal that intestinal phagocytes sense fungal dysbiosis and mediate gut-lung-directed immunity to aggravate allergic airway disease.",
keywords = "CX3CR1 mononuclear phagocytes, fungi, gut-lung axis, mycobiome, mycobiota dysbiosis",
author = "Xin Li and Irina Leonardi and Alexa Semon and Itai Doron and Gao, {Iris H.} and Putzel, {Gregory Garb{\`e}s} and Youngjun Kim and Hiroki Kabata and David Artis and Fiers, {William D.} and Ramer-Tait, {Amanda E.} and Iliev, {Iliyan D.}",
note = "Funding Information: This work was funded by the US National Institutes of Health (grants DK113136 and AI137157 to I.D.I.), Kenneth Rainin Foundation , Irma T. Hirschl Career Scientist award to I.D.I., and support from the Jill Roberts Institute for Research in Inflammatory Bowel Disease . We thank Dr. J. David Warren for assistance with the LC-MS/MS. ",
year = "2018",
month = dec,
day = "12",
doi = "10.1016/j.chom.2018.11.003",
language = "English (US)",
volume = "24",
pages = "847--856.e4",
journal = "Cell Host and Microbe",
issn = "1931-3128",
publisher = "Cell Press",
number = "6",
}