TY - JOUR
T1 - Rethinking ketamine as a panacea
T2 - adverse effects on oxygenation and postoperative outcomes
AU - Rolfzen, Megan L.
AU - Palanca, Ben Julian A.
AU - Bartels, Karsten
N1 - Publisher Copyright:
© 2024 British Journal of Anaesthesia
PY - 2024/4
Y1 - 2024/4
N2 - Ketamine is receiving renewed interest in perioperative medicine as an anaesthetic adjunct and a treatment for chronic conditions, including depression. Ketamine's complex pharmacologic profile results not only in several desirable effects, such as anaesthesia and analgesia, but also multiple adverse effects affecting the central nervous, cardiovascular, and respiratory systems. In addition to defining patient-centred outcomes in future clinical studies on the perioperative uses of ketamine, careful monitoring for its numerous adverse effects will be paramount.
AB - Ketamine is receiving renewed interest in perioperative medicine as an anaesthetic adjunct and a treatment for chronic conditions, including depression. Ketamine's complex pharmacologic profile results not only in several desirable effects, such as anaesthesia and analgesia, but also multiple adverse effects affecting the central nervous, cardiovascular, and respiratory systems. In addition to defining patient-centred outcomes in future clinical studies on the perioperative uses of ketamine, careful monitoring for its numerous adverse effects will be paramount.
KW - adverse effects
KW - hypoxaemia
KW - ketamine
KW - perioperative outcomes
UR - http://www.scopus.com/inward/record.url?scp=85185167590&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85185167590&partnerID=8YFLogxK
U2 - 10.1016/j.bja.2023.12.030
DO - 10.1016/j.bja.2023.12.030
M3 - Editorial
C2 - 38272733
AN - SCOPUS:85185167590
SN - 0007-0912
VL - 132
SP - 635
EP - 638
JO - British Journal of Anaesthesia
JF - British Journal of Anaesthesia
IS - 4
ER -