Abstract
Immunocytochemistry was used to identify infected cells after injection of Herpes simplex virus (HSV) into the superior colliculus, hypothalamus and optic chiasm. Ganglion cells of the retina were labeled in a pattern consistent with known projections to retinorecipient nuclei. Cells of both inner and outer nuclear layer were labeled. If this represents retrograde transneuronal transport, then HSV may provide an important tool for studying the neuronal circuitry of the retina.
Original language | English (US) |
---|---|
Pages (from-to) | 374-378 |
Number of pages | 5 |
Journal | Brain Research |
Volume | 479 |
Issue number | 2 |
DOIs | |
State | Published - Feb 13 1989 |
Externally published | Yes |
Keywords
- Hamster
- Herpes simplex virus
- Retina
- Superior colliculus
- Suprachiasmatic nucleus
- Transneuronal labeling
ASJC Scopus subject areas
- Neuroscience(all)
- Molecular Biology
- Clinical Neurology
- Developmental Biology